Interesting Biohub conversation with No Priors, Priscilla, and Alex Rives. We covered our latest release of a world model for protein biology (ESM) and what it means to do frontier biology alongside frontier AI. 10 years ago we set a goal to help the scientific community cure or prevent all diseases this century. With new AI advances, I'm optimistic we'll be able to get there a lot sooner. https://open.spotify.com/episode/2bufgHVuFxdBr6vKUkItdg?si=2Ap4WgeGTou8MCwUVlhoaw
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Mark Zuckerberg is the founder and CEO of Meta — the company behind Threads itself — and posts about Meta's products, AI work, and his MMA training.
America is going to need hundreds of thousands of skilled tradespeople to build the infrastructure for our country to lead in AI. People need access to the education and opportunity to secure these jobs. We believe the future is for everyone. Today, we're launching America's Workforce Academy with academic and workforce partners to provide free training and direct pathways to jobs building this infrastructure.
We want to deliver personal superintelligence for everyone -- and we want as many people as possible to help build that future with us. Check it out: https://about.fb.com/news/2026/06/americas-workforce-academy-free-skilled-trade-training/
Today Biohub is sharing a major scientific advance: our first world model for protein biology. This system can help scientists discover and design proteins that will hopefully lead to new medical therapies.
This release consists of two AI models and an atlas: ESMC, our state-of-the-art language model that represents proteins; ESMFold2, designed to transform ESMC’s sequence representations into atomically resolved 3D structures; and ESM Atlas, a dataset and tool that makes these representations navigable across 6.8 billion protein sequences. All are openly available at biohub.ai/esm/protein so scientists everywhere can use them and build on them.
Today we're starting to roll out Incognito Chat with Meta AI on WhatsApp and the Meta AI app -- a completely private way to interact with AI, similar to how end-to-end encryption means no one can read your conversations, even Meta or WhatsApp. This is the first major AI product where there is no log of your conversations stored on servers.

Incognito Chat handles all AI inference in a Trusted Execution Environment that ensures your messages are not accessible to us. The conversations on your phone also disappear when you exit the session. This is different from other disappearing AI products where your conversations logs often remain on other companies' servers for many months.
To get the most from personal superintelligence, we'll all need ways to discuss sensitive topics in ways that no one else can access. I'm proud that MSL is the first lab to deliver private AI.
As part of our philanthropic work to help cure all diseases, our team @biohub is announcing the Virtual Biology Initiative -- a new effort to build the imaging tools, molecular tools, and open data infrastructure needed to build AI models that can reason about cells.
This has the potential to unlock developing models that understand biology -- that can predict the outcomes of experiments before you run them, simulate the effects of drugs on diseased cells, and more. Excited to see what people build with it. https://biohub.org/news/virtual-biology-initiative
Today we're sharing our new model family, Muse, and releasing our first model, Spark. You can try them in Meta AI.
Meanwhile at Meta HQ

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